Lepromin皮肤测试是什么？
一个lepromin skin test is used to determine the type of Hansen’s disease (leprosy) a person has contracted. The lepromin skin test is also called the leprosy skin test.
Leprosy, also known as Hansen’s disease, is a long-term (chronic) condition caused by the bacteria麻风杆菌. The disease is commonly found in Asia and Africa and is transmitted through mucus or secretions from the nose, eyes, and mouth of an infected person. The disease has a long incubation time. The symptoms usually don’t begin for more than a year and progress slowly.
汉森氏病影响身体的以下部位：
- 皮肤
- 神经
- eyes
- upper respiratory tract
In men, the disease can affect the testes.
汉森氏病过去在全球范围内是一个重大的公共卫生问题。但是，那
The disease can be effectively treated and even cured if it’s caught in the early stages. Once Hansen’s disease has been diagnosed, your doctor must determine which type of汉森病you have to develop a treatment plan.
The symptoms of Hansen’s disease include:
- 皮肤病变几周或几个月无法愈合
- 皮肤lesions that are lighter in color or are less sensitive to heat, pain, or touch than unaffected skin
- 皮肤thickening or scarring
- nerve damage leading to numbness or lack of sensation in the extremities
- 随着时间的流逝，肌肉的弱化
皮肤活检通常用于诊断汉森病。一个皮肤活检involves removing a small section of skin for laboratory testing. If you have the symptoms of Hansen’s disease, a lepromin skin test may be ordered along with a biopsy to confirm both the presence and type of leprosy.
There are several types of汉森病从轻度（不确定）到严重（松性）。根据疾病的临床特征，汉森病可能被归类为：
- indeterminate Hansen’s disease
- 结核病汉森病
- 边缘结核病汉森病
- borderline Hansen’s disease
- borderline lepromatous Hansen’s disease
- lepromatous Hansen’s disease
Your doctor must determine which type of Hansen’s disease you have to provide the correct treatment.
一个lepromin skin test is performed by injecting a small sample of inactivatedM. Leprae在你的皮肤下。“灭活”一词意味着细菌无法引起感染。通常将细菌注入前臂。注射部位会形成一个小肿块，表明正确量的细菌已在皮肤中的正确深度注射，以使测试有效。
注射后三天需要检查您是否对细菌有反应。如果没有发生反应，则需要在28天内再次检查您。注射部位的特定反应表明某些类型的汉森病。
该测试无需准备。如果您患有皮肤刺激或皮肤疾病，例如皮炎，应在不受影响的皮肤的一部分上进行注射。皮肤redness或由于皮肤疾病无关而引起的刺激可能会在雷皮明皮肤测试中产生假阳性结果。在未受影响的区域上进行测试将有助于确保测试准确。
与Lepromin皮肤测试相关的风险很小。注射可能会引起轻微的燃烧或刺痛感。注射部位在注射后也可能发痒。
在非常罕见的情况下，注射后可能会发生过敏反应。过敏反应可能导致呼吸急促和瘙痒。Hivescan also occur, but this is rare.
如果发生这些症状，请从医生那里得到帮助，以确保反应不严重。
The results of the lepromin skin test are based on changes in the skin that occur at the injection site. Redness, swelling, or other skin changes indicate the presence of tuberculoid and borderline tuberculoid Hansen’s disease. If you’ve tested positive for Hansen’s disease during a biopsy but don’t have a skin reaction, you may have lepromatous Hansen’s disease.
If your biopsy and skin test indicate that you have any form of Hansen’s disease, your doctor will most likely prescribe the antibiotics dapsone, rifampin (Rifadin), and clofazimine (Lamprene), which you may have to take for months or even years to treat the disease.