Introduction

剧烈的疼痛可以unbearabl日常活动e or even impossible. Even more frustrating is having severe pain and turning to medications for relief, only to have the drugs not work. If this happens, take heart. There are stronger medications available that may ease your pain even after other drugs failed to work. These include the prescription drugs Opana and Roxicodone.

Opana和Roxodoone都在一类称为阿片类镇痛药或麻醉品的药物中。在其他药物没有努力缓解疼痛之后，它们被用来治疗中度至严重的疼痛。两种药物都在大脑中的阿片类药物受体上起作用。通过对这些受体作用，这些药物改变了您对疼痛的看法。这有助于使您感到痛苦。

The following table gives you a side-by-side comparison of some of the features of these two drugs.

品牌 OPANA 罗毒酮
什么是通用版本？ oxymorphone 羟考酮
它对待什么？ 中度至严重的疼痛 中度至严重的疼痛
What form(s) does it come in? 即时释放平板电脑，扩展释放片，扩展释放的注射溶液 immediate-release tablet
这种药物有什么优势？ 立即发行的平板电脑：5 mg, 10 m,
扩展释放平板电脑：5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 m
extended-release injectable solution:1 mg/mL		 5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg, 30 mg
什么是典型剂量？ immediate release:5-20 mg every 4-6 hours,
extended release:5 mg every 12 hours		 immediate release:5-15 mg every 4-6 hours
How do I store this drug? 存放在59°F和86°F之间的干燥位置（15°C和30°C） 存放在59°F和86°F之间的干燥位置（15°C和30°C）

Opana是通用药物矛盾的名牌版本。罗毒酮是通用药物羟考酮的品牌名称。这些药物也可以作为通用药物使用，并且都具有即时释放版本。但是，也只有OPANA以扩展释放的形式可用，并且只有Opana以可注射的形式提供。

两种药物治疗的长度取决于您的疼痛类型。但是，不建议长期使用以避免成瘾。

Both medications are controlled substances. They’re known to cause addiction and can be abused or misused. Taking either medication not as prescribed can lead to overdose or death.

Your doctor may monitor you for signs of addiction during your treatment with Opana or Roxicodone. Ask your doctor about the safest way to take these medications. Don’t take them for longer than prescribed.

At the same time, you should also never stop taking Opana or Roxicodone without talking to your doctor. Stopping either drug suddenly can cause withdrawal symptoms, such as:

  • 不安
  • irritability
  • 失眠
  • sweating
  • 发冷
  • 肌肉和关节疼痛
  • 恶心
  • vomiting
  • diarrhea
  • 血压升高
  • increased heart rate

When you need to stop taking Opana or Roxicodone, your doctor will slowly lower your dosage over time to decrease your risk of withdrawal.

OPANAand Roxicodone are both available as generic drugs. The generic version of Opana is called oxymorphone. It’s more expensive and not as readily available at pharmacies as oxycodone, the generic form of Roxicodone.

Your health insurance plan will likely cover the generic version of Roxicodone. However, they may require you to try a less-powerful drug first. For brand name versions, your insurance may require a prior authorization.

OPANAand Roxicodone work in the same way, so they cause similar side effects. The more common side effects of both drugs include:

  • 恶心
  • vomiting
  • constipation
  • headache
  • 瘙痒
  • drowsiness
  • dizziness

The following table highlights how the more common side effects of Opana and Roxicodone differ:

Side effect OPANA 罗毒酮
发烧 X
Confusion X
睡眠麻烦 X
Lack of energy X

The more serious side effects of both drugs include:

  • slowed breathing
  • 停止呼吸
  • cardiac arrest (stopped heart)
  • 低血压
  • 震惊

OPANA和ROXOXODONE具有类似的药物相互作用。始终在开始治疗新药之前服用所有处方和非处方药，补充剂和草药。

If you take either Opana or Roxicodone with certain other drugs, you may have increased side effects because certain side effects are similar between the drugs. These side effects can include breathing problems, low blood pressure, extreme tiredness, or coma. These interacting medications include:

  • other pain medications
  • 势噻嗪（用于治疗严重精神疾病的药物）
  • monoamine oxidase inhibitors (MAOIs)
  • 镇静剂
  • 安眠药

其他药物也可以与这两种药物相互作用。有关这些交互的更详细列表，请参阅OPANA的相互作用和Roxoxodone的交互。

OPANAand Roxicodone are both opioids. They work similarly, so their effects on the body are also alike. If you have certain medical issues, your doctor may need to change your dosage or schedule. In some cases, it may not be safe for you to take Opana or Roxicodone. You should discuss the following health conditions with your doctor before taking either drug:

  • 呼吸问题
  • 低血压
  • history of head injuries
  • 胰腺或胆道疾病
  • 肠道问题
  • 帕金森氏病
  • liver disease
  • 肾脏疾病

两种药物都在治疗疼痛方面非常有效。您的医生会选择最适合您和您的疼痛的药物D在您的病史和痛苦水平上占。

如果您患有中度至重度疼痛，即使尝试止痛药后也不会放松，请与您的医生交谈。询问Opana或Roxoxodone是否适合您。两种药物都是非常强大的止痛药。他们以类似的方式工作，但有明显的差异：

  • Both drugs come as tablets, but Opana also comes as an injection.
  • Only Opana is also available in extended-release forms.
  • Generics of Opana are more expensive than generics of Roxicodone.
  • They have slightly different side effects.