丙型肝炎治疗在缓解方面非常有效。丙型肝炎缓解中的一个人在上次治疗后12或24周没有可检测到的病毒量。

Hepatitis C infection can be acute or chronic. Acute infections last for less than 6 months ，而慢性丙型肝炎可能是终生的疾病。

大致 5800万 根据世界卫生组织（WHO）的数据，全球人患有慢性丙型肝炎。在这个数字中，疾病控制和预防中心报告了估计的 2.4 million Americans have chronic hepatitis C and that there are around 50,300 new cases of acute hepatitis C in the United States annually.

在美国，注射药物是获得丙型肝炎的主要危险因素。未经治疗的丙型肝炎可能导致严重的肝脏问题，包括肝硬化和癌症。

重要的是要知道该病毒可以通过正确的治疗方法缓解。医生将缓解称为持续的病毒学反应（SVR）。

svrmeans that blood tests cannot detect the hepatitis C virus 12周 在一个人的最后治疗剂量之后。此后，该病毒可能永久消失。医生可以在24周再次检查病毒。相近99%of people who achieve an SVR remain virus-free, according to the U.S. Department of Veterans Affairs.

Typically, people who reach SVR:

  • experience improvement in liver inflammation
  • have decreased or regressed fibrosis
  • are twice as likely to have lower inflammation scores
  • 死亡率，肝衰竭和肝癌的风险降低
  • 发展其他医疗状况的机会减少了

但是，肝损伤和纤维化的持续程度将影响这些生理改善。SVR时有明显纤维化的人可能 需要进行持续的监视 for liver complications.

People who recover from hepatitis C are at an increased risk of liver disease progression if other risk factors are present, such as alcohol use disorder, obesity, and diabetes.

Acute and chronic hepatitis C infections may resolve independently. However, this is incredibly rare in chronic cases.

急性肝炎的自发病毒清除率

Spontaneous viral clearance of acute infections is possible. However, the rate at which this occurs is a hotly debated topic, as most cases 疾病预防控制中心称，急性丙型肝炎变为慢性。

Current research estimates that acute cases of hepatitis C resolve spontaneously in 15％至60％的案件 。

慢性丙型肝炎的自发缓解

对于某些人来说，慢性丙型肝炎也可以自行清除，但这非常罕见。2016年的一项苏格兰研究发现，自发性慢性乙型肝炎的缓解率可能是as low as 0.36%。

慢性丙型肝炎c always requires 药物治疗。任何有病情的人都需要从医疗保健专业人员那里进行持续的监控，并应始终遵循其治疗计划才能完成。

药物治疗可以帮助增加你的机会reaching hepatitis C virus remission. Your treatment plan will depend on:

  • Genotype:您的丙型肝炎基因型或病毒的“蓝图”取决于您的RNA序列。有 seven genotypes , and most people in the U.S. have genotype 1, per the CDC.
  • 肝损害：现有的肝脏损害，无论是轻度或重度，都可以确定您的药物。
  • Previous treatment:Which medications you already take will also influence next steps.

共感染和病毒相互作用

Other conditions, such as HIV and hepatitis B, can alter your treatment plan.

For example, having hepatitis C and B infections simultaneously can speed up disease 进展和两种疾病的抗病毒治疗也可以重新激活另一个。此外，某些丙型肝炎治疗可能不合适for people with HIV due to possible drug interactions.

To prevent adverse outcomes, your doctor will screen for possible coinfections and alter your medication programs accordingly.

Medications

在查看了这些因素之后，医疗保健专业人员将开一些药物供您服药 12 to 24 weeks ，根据谁。您可能需要服用这些药物更长的时间。您可以与您的医生交谈，以了解有关特定治疗计划的详细信息的更多信息。

Drugs for hepatitis C may include:

  • Daclatasvir（Daklinza）与Sofosbuvir（Sovaldi）
  • sofosbuvir with velpatasvir (Epclusa)
  • Ledipasvir/sofosbuvir (Harvoni)
  • simeprevir (Olysio)
  • boceprevir (Victrelis)
  • Ledipasvir
  • ribavirin (Ribatab)

You may hear some of the newer drugs referred to as direct-acting antiviral (DAA) medications. These target virus replication at specific steps of the hepatitis C life cycle. Your doctor may prescribe other combinations of these drugs.

如果您遇到不适或药物副作用，请与您的医生交谈。如果您经历抑郁症的感觉，请寻求支持。您的医生可能会有患者倡导资源来提供支持，以帮助您通过治疗，并达到摆脱乙型肝炎的目标。

实现SVR后的丙型肝炎复发是很少见的。实际上，DAA治疗后乙型肝炎复发的机会小于 0.5% 。

丙型肝炎复发可能是由于复发或再感染。复发是SVR后病毒的独立回归，非常罕见。当外部因素将丙型肝炎病毒重新引入您的系统时，就会重新感染。

作者2016 reviewidentified risk factors for reinfection as:

  • 目前或以前注射药物
  • men who have sex with men
  • coinfections, especially ones that compromise your immune system

复发率还可以取决于基因型，药物方案以及是否有其他现有疾病等因素。

医生可以通过血液检查诊断丙型肝炎。通常，您越早获得诊断并开始治疗，结果就越好。

丙型肝炎治疗容易获得，并且在缓解缓解方面非常有效。缓解是在您上次治疗后12到24周不再在血液中检测到的病毒。

The hepatitis C genotype, the extent of liver damage, and any preexisting conditions or infections can all affect treatment options. However, the outlook for hepatitis C treatments is typically positive.