Ceruloplasmin is a glycoprotein that’s produced in the liver.

It carries or transports the majority of copper in the blood.

Copperplays an important role in the body by aiding crucial bodily processes. These include producing energy, forming connective tissue, and helping yourcentral nervous system (CNS)function.

A ceruloplasmin test can determine the levels of ceruloplasmin in your body. The test is most often used to diagnoseWilson’s disease, a rare genetic disorder.

Wilson’s disease causestoo much copperto collect in the liver, the brain, and other body tissues and organs. It’s also known as hepatolenticular degeneration.

Your doctor may order a ceruloplasmin test if you have symptoms of Wilson’s disease. Symptoms of Wilson’s disease are primarily hepatic (or liver-related), neurological, and psychiatric and may include:

Your doctor will usually order the ceruloplasmin test along with other blood and urine copper tests to confirm your diagnosis.

If you’ve already been diagnosed with Wilson’s disease, your doctor may order the ceruloplasmin test to determine if your treatment is working.

For the ceruloplasmin test, you’ll be required to provide a blood sample.

A healthcare professional willuse a needle to extract blood从你的手臂。The blood will be collected in a tube and sent to a lab for analysis.

Once the lab reports the results, your doctor will be able to provide you with more information about the results and what they mean.

If you have a ceruloplasmin test, you may experience some discomfort when the blood sample is drawn. Needle sticks may result in mild pain during the test.

In general, the risks of a ceruloplasmin test are minimal. These risks are common to most routine blood tests. Potential risks include:

  • difficulty obtaining a sample, resulting in multiple needle sticks
  • excessive bleeding at the puncture site
  • 晕倒的失血
  • the accumulation of blood under the skin, known as a hematoma
  • the development of askin infectionwhere the needle breaks the skin

There’s usually no preparation required for the ceruloplasmin test. Ask your doctor if there’s anything special you need to do before the test.

According to StatPearls , the normal ranges for serum ceruloplasmin for people who are at least 20 years old are:

  • men:22 to 40 milligrams per deciliter (mg/dL)
  • women who don’t take oral contraceptives:25 to 60 mg/dL
  • women who take oral contraceptives or estrogen:27 to 66 mg/dL
  • pregnant people:30 to 120 mg/dL

Young children tend to have higher ceruloplasmin blood levels than older children and adults. For example, the normal range for children between 7 months old and 3 years old is 31 to 90 mg/dL.

Your ceruloplasmin test results will vary based on the lab that completes the analysis of your blood. Talk with your doctor about your results and what they mean.

If your ceruloplasmin levels are lower than normal, it may indicate the presence of Wilson’s disease.

Low levels of ceruloplasmin

Other health problems may also cause your ceruloplasmin levels to be low. These include:

High levels of ceruloplasmin

血浆铜蓝蛋白水平可能高于诺玛l if you’re:

  • pregnant
  • taking estrogen
  • taking a combination birth control pill, which is anoral contraceptivethat contains estrogen and progesterone

Manyinflammatory conditionsorneoplastic diseasescan also lead to high levels of ceruloplasmin. Neoplastic diseases are ones that cause abnormal tissue growth.

If your ceruloplasmin levels are high, it could also indicate that you have:

It’s important to note that the ceruloplasmin test isn’t typically used to diagnose most conditions that cause abnormal levels of ceruloplasmin. It’s mostly used if someone has symptoms of Wilson’s disease.

Treatment for Wilson’s disease typically begins with medications that help reduce the level of copper in your organs. In later stages,zincmay also be prescribed. High levels of zinc can inhibit copper absorption.

If the test reveals any other abnormalities, your doctor will help interpret your results. Either way, they may want to do some follow-up testing.