- A new genetic analysis provides more evidence that high blood pressure is a leading risk factor for atrial fibrillation.
- 以前的研究表明，两个条件是链接的。现在，一项新的研究为高血压提供了更强的支持作为驱动因子。
- Treating high blood pressure will likely help reduce the risk of atrial fibrillation.
一个新的遗传学研究提供了额外的证据，即高血压或高血压可能导致心房颤动（AFIB），最常见的不规则性节律类型。
While previous research has shown that the two conditions are linked, thenew study, published online Feb. 9 in the European Journal of Preventive Cardiology, provides stronger support for high blood pressure as the driving factor.
“高血压和心房颤动之间的连接得到了很多年的很多少年，”说托德博士赫尔特博士, a cardiologist at Banner – University Medicine Heart Institute. He wasn’t involved in the new study.
“While this study is a novel approach to showing causality and not just association, its primary benefit is in re-emphasizing the importance of high blood pressure as a cause of AFib,” he said.
An estimated 12.1 million people in the United States will have AFib in 2030, according to the
In addition to causing an irregular heart rate, this condition can lead to lightheadedness, extreme fatigue, shortness of breath, and chest pain.
AFib also increases the risk of stroke, accounting for about
Earlier
然而，由于设计了早期的研究，结果没有提供这两个条件如何相关的完整图片。
“以前的观察性研究对心房颤动有相关的高血压，”说维多利亚博士, a cardiologist with Torrance Memorial Medical Center. “Until this study, however, we weren’t sure if hypertension was a原因心房颤动......或只是它保持的公司。“
复杂的东西，这两个条件都有许多相同的风险因素 - 包括较老年，肥胖，糖尿病和炎症 - 这可以解释为什么高血压和AFIB经常一起发生。
To gain a better understanding of how the two conditions are related, the authors of the new study examined genetic data from more than 1 million people of European ancestry.
Their analysis suggests that when both conditions occur together, high blood pressure is likely the cause of AFib.
This would mean that in many cases, AFib is preventable through medication and lifestyle changes that reduce high blood pressure.
“Together with other [similar genetic] studies, our findings confirm the hypothesis that [AFib] is preventable,” wrote the authors in the new study.
Shin said the size of this new study group was impressive. In addition, the use of genetic analysis to explore the link between high blood pressure and AFib — and to take into account other risk factors — was an “innovative” approach.
However, Shin cautions that because participants included in the study were all of European descent, the results may not apply directly to other racial or ethnic groups.
Dr. David Stuhlmiller，Rwjbarnabas Health Requarty和Houthary Storage Services和Robert Wood Johnson University Rahway表示，这项研究在医学上进行了意义，鉴于我们对AFIB的原因所了解。
“我们理解心房颤动是由心脏的伸展引起的，”他说。这个可以伸展肌肉并通过心脏破坏电信号的传导。
“由于高血压延伸了心脏的肌肉，”他说，“它自然遵循的是，高血压可能有助于心房颤动的发展。”
然而，StuhlMiller表示研究了一定的局限性。
一，研究人员没有提供有关学习参与者是否接受高血压治疗的信息，例如β-阻滞剂或血管紧张素转换酶（ACE）抑制剂。
通过减少血压，这些治疗可能会降低一个人的发展交通界的风险，这可能影响了遗传分析的结果。
此外，STUHLMILLER表示，如果作者能够展示血压有多少，这项研究将更有用的临床收缩系统和舒张性— would need to be lowered to reduce a person’s risk for AFib.
High blood pressure isn’t just a risk factor of AFib. It’s also a
This makes managing high blood pressure an important health goal for anyone, but especially for people who already have AFib.
“For those with AFib, it’s critically important to know that treating blood pressure — in addition to being physically active, treating sleep apnea, avoiding excess alcohol, and weight loss for those who are overweight — is a remarkably effective strategy for treating AFib,” Hurst said.