Researchers are looking at the proteins that help the body make teeth as a way to fix cavities without using a dentist’s drill.
There’s a new dental product that uses your body’s natural tooth-forming proteins to rebuild tooth enamel to repair cavities.
你为什么要关心？嗯，这个过程可以取代填充牙腔的当前方法...而不使用钻头。
The product was the subject of a research study that was published recently in the journalACS生物材料科学与工程.
根据这一点
Dental cavities can seriously impact quality of life.
Among other things, cavities may make eating painful and disrupt sleep. When they reach an advanced stage (abscess), cavities may even cause chronic systemic infection.
发表的2015年研究Journal of Dental Research2.4发现蛀牙的影响billion people worldwide.
In addition, untreated cavities in baby teeth were the 10thmost prevalent condition, affecting more than 600 million children globally.
Untreated, tooth decay will eventually lead to tooth loss.
根据疾病控制和预防的中心（CDC），
Dr. Shantanu Lal, director of predoctoral pediatric dentistry and an associate professor of dental medicine at Columbia University Medical Center in New York, told Healthline “Untreated cavities in baby teeth can lead to serious consequences that include pain, learning difficulties, difficulty chewing, poor sleep, missed hours at school, and potentially, life-threatening dental inflammation and infection.”
Many of the foods we eat cause bacteria in the mouth to create acids.
Foods with lots of sugar are well-known sources of plaque, but starches such as bread, crackers, and cereal can also make acids form.
“细菌在口腔环境中代谢糖和其他可发酵的碳水化合物，作为副产品，将使牙釉质脱矿物，”华盛顿大学恢复牙科部门的研究共同作者和助理教授萨米·多诺牙科学院在新闻稿中说。
细菌也负责牙菌斑，可以刺激口香糖，使它们变红，易于出血，敏感，并受口香糖疾病。
Gum disease can cause the gums to recede from teeth, making pockets that fill with the bacteria that cause infection.
没有治疗，牙齿周围的骨骼可能会劣化，松动牙齿和超速衰减。
Researchers at the University of Washington School of Dentistry were inspired by how the body’s natural tooth-forming proteins work.
So, they came up with a method to repair damaged tooth enamel. They captured the essence of amelogenin, the protein needed to form crown enamel, and designed amelogenin-derived peptides (part of a cell that carries out important functions) that can repair tooth enamel.
这些肽是这种新治疗中的活性成分。修复看起来就像身体牙釉质中发现的矿物结构一样。
“Remineralization guided by peptides is a healthy alternative to current dental health care,” said Mehmet Sarikaya, a lead study author and professor of materials science and engineering and adjunct professor in the Department of Chemical Engineering and Department, said in a新闻稿.
TheAmerican Dental Association (ADA) states on their website that “The formerly practiced paradigm of ‘drill and fill,’ drilling out pits and fissures or surgically removing decayed and diseased tissue and placing permanent restorations, does not address the full continuum of the caries disease process, including microbial activity and the balance between enamel remineralization and demineralization.”
虽然它仍在开发中，研究人员预期这一新处理将用于公共和私人健康环境。
This treatment could eventually be incorporated into toothpastes, gels, and other dental care products as a safe, healthy alternative to current dental treatments and procedures that can be used by adults and children.
这项技术可以通过作为牙科护理程序的一部分重建和加强牙釉质来阻止人们防止人们每天重建和加强牙釉质。
然而，LAL注意事项“用生物方法处理的空腔将需要通过牙科专业人士进行仔细和频繁的监测，并且应在负责在患者人群中使用之前的临床试验进行验证。不应建议在进行进一步调查这种治疗的所有潜在风险之前的家庭护理。“