肌钙蛋白是心肌肌肉中发现的蛋白质。当心脏受损时，它将肌钙蛋白释放到血液中。
Doctors measure your cardiac troponin levels to help detect whether you’re experiencing a heart attack. A troponin test can also help doctors find the best treatment sooner.
以前，医生使用其他血液测试（如CPK同工酶测试) to detect aheart attack. But they aren’t always the optimal test because they aren’t sensitive enough to detect every attack. Smaller heart attacks leave no trace on these blood tests. The other tests also measure substances that aren’t specific enough to the heart muscle.
肌钙蛋白更敏感。测量血液中的心肌肌钙蛋白水平使医生更有效地诊断心脏病发作或其他心脏相关的条件，并提供即时治疗。
Troponin levels are measured with a标准血液测试. A healthcare professional will take a sample of your blood from a vein in your arm. You can expect mild pain and maybe light bruising.
After taking the blood sample, the healthcare professional will assess your troponin levels to diagnose a heart attack. They’ll also look for any changes on anelectrocardiogram (ECG or EKG), an electrical tracing of your heart.
These tests may be repeated several times over a 24-hour period to look for changes.
与传统的肌钙蛋白测试,它可以把侯rs before increased levels of troponin are detectable. Using this test too soon can produce a false negative.
A high-sensitivity troponin test is also available. This test can detect elevated troponin levels and produce positive test results inas little as 9 minutes.
If your troponin levels are low or normal after experiencing胸痛, you probably have not experienced a heart attack. If your levels are high, the likelihood of heart damage or heart attack is high.
Related tests
In addition to measuring your troponin levels and monitoring your ECG or EKG, the healthcare professional may want to perform other tests to examine your health, including:
- additional blood tests to measurecardiac enzyme levels, inflammation marker or clotting markers
- blood tests for other medical conditions
- an超声心动图, an ultrasound of the heart
- achest X-ray
- aCT scan
Troponin proteins help regulate muscle contraction. They’re split into three subunits:
- troponin C (TnC), which binds tocalcium, initiates muscle contraction, and helps move TnI
- troponin I (TnI)，它与TNC一起拉动肌肉纤维
- troponin T (TnT)，将肌钙蛋白蛋白锚定到一个叫做冠状阴胞素的单独蛋白质
肌钙蛋白测试测量TNI或TNT的水平。
Your doctor will recommend this test if you’re experiencing chest pain or relatedheart attack symptoms, including:
Troponin levels are measured in nanograms per milliliter (ng/mL). High-sensitivity tests measure troponin levels in nanograms per liter (ng/L).
Normal levels fall below the 99th percentile in the blood test. If troponin results are above this level, it may indicate heart damage or heart attack. Reference ranges for troponin levels will vary by test lab.
A2017 studysuggests that women may have lower cardiac troponin levels than men. As a result, women can experience heart damage from a heart attack at levels below the current “normal” cutoff for some labs. In other labs, what’s considered normal may differ for men and women.
如果它们是升高的TNI水平通常被认为是升高的
If your troponin levels are low or normal
In healthy people, troponin levels are within the normal range. If you’ve experienced chest pain, but troponin levels are still low or normal胸痛开始后12小时, the possibility of a heart attack is unlikely.
If your troponin levels are high
High levels of troponin are an immediate red flag. The higher the troponin levels, the more troponin — specifically TnI and TnT — that’s been released into the bloodstream and the higher the likelihood of heart damage. Troponin levels can become elevatedwithin 3 to 6 hoursafter the heart’s been damaged and can remain high for 10 to 14 days.
Though a rise in troponin levels is often an indication of a heart attack, there are a number of other reasons why your troponin levels could be elevated.
Troponin levels can be acutely elevated or chronically elevated. If you’re experiencing symptoms in addition to a change in troponin levels, a healthcare professional will use your symptoms to help inform their diagnosis.
可以促进高肌钙蛋白水平的其他心脏病包括：
- myocarditis, which is inflammation of the heart muscle
- 心包炎, which is inflammation of the sac of the heart
- endocarditis, which is inflammation of the inner layer of the heart
- cardiomyopathy, which is a weakened heart
- heart failure
- stable angina, which is a type of chest pain caused by poor blood flow to the heart
Other possible causes of high troponin levels include:
- intense exercise
- burns
- medications, likemetoprolol(Toprol XL, Lopressor)
- stroke
- diabetes
- kidney disease
- pulmonary embolism, which is a blood clot in your lungs
- hypothyroidism, which is an underactive thyroid
- intestinal bleeding
- an extensive infection, likesepsis
Did you know?High-sensitivity troponin tests can detect elevated troponin levels in people without symptoms of cardiovascular disease, according to a
2019 study . This means the test results can be used to help predict whether you’re at increased risk for a future cardiac event, like aheart attack要么stroke.
Troponin is a protein released into your blood after you experience a heart attack. High troponin levels can be indicators of other heart conditions or illnesses, too.
If you begin to experience chest pain orsuspect you’re having a heart attack, call 911 or your local emergency services. Heart attacks and other heart conditions can be fatal.
All chest pain should be evaluated in an emergency room. Self-diagnosis is never recommended.
Lifestyle changes and treatment can help improve your heart health as well as your quality of life..