Overview

亚临床甲状腺功能亢进是一种你有低的状况甲状腺刺激激素（TSH）的水平but normalT3的水平一个dT4.。

T4.(thyroxine) is a major hormone secreted by your甲状腺。T3.(triiodothyronine) is a modified version of T4. The amount of T4 produced by your thyroid gland is controlled by the levels of TSH production by yourpituitary gland一个d vice versa.

Therefore, if your pituitary gland sees very little T4, it will produce more TSH to tell your thyroid gland to produce more T4. Once the amount of T4 reaches appropriate levels, your pituitary gland recognizes that and stops producing TSH.

在亚临床甲状腺功能亢进的人中，甲状腺产生正常水平的T4和T3。然而，它们具有低于正常的TSH水平。这种对荷尔蒙的这种不平衡导致了这种情况。

估计一般人群亚临床甲状腺功能亢进症的患病率估计为范围0.6 to 16 percent。这取决于所使用的诊断标准。

大多数有亚临床甲状腺功能亢进的人都没有症状overactive thyroid。如果存在亚临床甲状腺功能亢进症的症状，它们是轻度和非特异性的。这些症状可以包括：

  • rapid heartbeat or heart palpitations
  • tremors, typically in your hands or fingers
  • sweating or intolerance to heat
  • 紧张,焦虑,或感觉irritable
  • weight loss
  • difficulty concentrating

Subclinical hyperthyroidism can be caused by both internal (endogenous) and external (exogenous) factors.

Internal causes of subclinical hyperthyroidism can include:

  • 坟墓疾病。坟墓疾病is an autoimmune disorder that causes an overproduction of thyroid hormones.
  • 多个透迹。An enlarged thyroid gland is called a goiter. Amultinodular goiteris an enlarged thyroid where multiple lumps, or nodules, can be observed.
  • Thyroiditis.Thyroiditis是甲状腺的炎症，包括一组病症。
  • 甲状腺腺瘤。A thyroid adenoma is a良性肿瘤of the thyroid gland.

亚临床甲状腺功能亢进的外部原因包括：

  • excessive TSH-suppressive therapy
  • unintentional TSH suppression during hormone therapy forhypothyroidism

Subclinical hyperthyroidism can occur in pregnant women, particularly in the first trimester. However, it’s 无关 具有不良妊娠结果，通常不需要治疗。

如果你的医生怀疑你有亚临床甲状腺功能亢进，他们首先会评估你的TSH的水平。

If your TSH levels come back low, your doctor will then evaluate your levels ofT4.一个dT3.看他们是否在正常范围内。

为了执行这些测试，您的医生需要从手臂上拍摄血液样本。

The normal reference range for TSH in adults is typically defined as 0.4 to 4.0 milli-international units per liter (mIU/L). However, it’s important to always refer to the reference ranges provided for you on the laboratory report.

Subclinical hyperthyroidism is generally classified into two categories:

  • Grade I:低，但可检测到的Tsh。此类别中的人在0.1到0.4 mlu / l之间的TSH水平。
  • Grade II:Undetectable TSH. People in this category have TSH levels less than 0.1 mlU/L.

当亚临床甲状腺功能亢进症未处理时，它对身体可能有几个负面影响：

  • 增加甲状腺功能亢进风险。有无法察觉的TSH水平的人都是如此 increased risk for developinghyperthyroidism。
  • Negative cardiovascular effects.未经治疗的人可以发展：

A review of scientific literature found that low TSH levels spontaneously returned to normal in 50％ 亚临床甲状腺功能亢进的人。

条件是否需要治疗取决于：

  • 原因
  • 它有多严重
  • 存在任何相关的并发症

基于原因的治疗

Your doctor will work to diagnose what may be causing your subclinical hyperthyroidism. Determining the cause can help determine the appropriate treatment.

治疗亚临床甲状腺功能亢进的内部原因

If you have subclinical hyperthyroidism due to Graves’ disease, medical treatment is required. Your doctor will likely prescribe radioactive iodine therapy or anti-thyroid medications, such as methimazole.

放射性碘治疗和抗甲状腺药物也可用于治疗由于多内胚胎或甲状腺腺瘤引起的亚临床甲状腺功能亢进。

Subclinical hyperthyroidism due to thyroiditis typically resolves spontaneously without any additional treatment required. If thyroiditis is severe, your doctor may prescribe anti-inflammatory drugs. These could include nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids.

治疗亚临床甲状腺功能亢进的外部原因

If the cause is due to TSH-suppressive therapy or hormone therapy, your doctor may adjust the dosage of these drugs where appropriate.

基于严重程度治疗

如果您的TSH水平低但仍然可检测并且您没有复杂，则可能无法立即进行治疗。相反，您的医生可以选择每隔几个月重新测试您的TSH级别，直到他们恢复正常或您的医生满足您的情况稳定。

Treatment may be required if your TSH levels fall into Grade I or Grade II and you’re in the following risk groups:

  • you’re over 65 years of age
  • 你有心血管疾病
  • 你有osteoporosis
  • 你有症状暗示甲​​状腺功能亢进症

Your treatment will depend on what type of condition is causing your subclinical hyperthyroidism.

治疗并发症

如果您由于您的亚临床甲状腺功能亢进症而经历心血管或与骨骼相关的症状，则可能会受益于β阻滞剂和双膦酸盐。

Somestudies已经表明，通过确保获得足够的每日剂量，可以减轻对骨密度的负面影响calcium。

如果您有亚临床甲状腺功能亢进，您可能会减肥。这是因为具有过度活跃的甲状腺的人具有升高的基础代谢率（BMR）。维持体重的卡路里要求将更高。

Subclinical hyperthyroidism is when you have low levels of TSH but have normal levels of T3 and T4. If you’re experiencing symptoms of subclinical hyperthyroidism, your doctor can use a series of blood tests to come to a diagnosis.

Since this condition can be caused by a variety of different conditions, the treatment you receive will depend on the cause and severity. Once your levels return to normal either naturally or through use of medication, your outlook should be excellent.