Lupus is a type of autoimmune disease. This means it causes your body’s immune system to attack healthy tissues and organs instead of only attacking foreign substances that could harm your body. The disease can cause widespread damage to areas of the body, including the joints, skin, heart, blood vessels, brain, kidneys, bones, and lungs.
有几种不同种类的狼疮,每种触发器略有不同。研究人员究竟不知道是什么原因导致狼疮,但我们知道遗传学发挥作用,并且在女性中更常见。
狼疮的大多数人在疾病过程中经历了某种类型的皮肤问题。皮肤参与和症状可能因您拥有的狼疮类型以及您的狼疮是多么活跃的而有所不同。
狼疮的迹象之一是在脸上开发皮疹。发红涵盖鼻子和脸颊,看起来像蝴蝶的形状。皮疹通常被称为蝴蝶疹,通常出现在脸上,但它也可以展示你的手臂,腿或身体的其他地方。
狼疮还导致你的皮肤对太阳或人工紫外线更敏感。未受保护的阳光暴露会导致环形标记,可以变为红色和鳞片状。这些可以在头皮和面部形成,或者像颈部或武器一样地曝光的其他区域。
溃疡或溃疡可以在脸颊或牙龈上嘴巴形成。它们还可以在鼻子,头皮或阴道组织上形成。这些疮可能不会受到伤害,或者他们可能会感到像溃疡。它们是来自疾病的炎症的迹象,并且可能是不舒服的。
sjogren的综合症is common in people with autoimmune disorders, like lupus. It causes your mouth and eyes to feel very dry. You might experience trouble speaking or swallowing, or have itchy, burning eyes.
干燥的嘴也可以让你处于更高的蛀牙的风险,因为唾液有助于保护牙齿免受细菌的影响。腔在牙龈线上发生,并强烈建议Sjogren的诊断。
有些人狼疮可能会遇到脱发,或者脱发. Lupus can cause hair to be dry or more brittle. Hair may break or fall out, particularly at the front of the forehead. The hair may grow back, or you may have permanent bald spots.
The pancreas is a gland behind the stomach that controls digestion enzymes and hormones that regulate how your body processes sugar. If it can’t work properly, you’re at risk of infection, digestive problems, and diabetes.
Lupus can cause inflammation of the pancreas, called pancreatitis, either from inflamed blood vessels or medications, like steroids or immunosuppressants used to treat the disease.
狼疮可以影响你的心脏和血管。人们Systemic Lupus红斑(SLE)患心脏病的风险较高。事实上,心脏病是狼疮人民最常见的死亡原因之一。
You’ll need to take extra precautions, like eating an anti-inflammatory diet and staying physically active in order to maintain healthy blood pressure and cholesterol levels.
狼疮还会导致动脉发炎。炎症会导致血管破裂并在组织内渗出,在于它们所在的组织内。当这种情况发生在较小的血管上,就像在皮肤中一样,唯一的症状可能是一些皮肤变色。在其他组织中,像大脑或心脏一样,出血血管可以成为一个主要的风险,并且潜在致命。炎症也可能导致感染。
Although less common, anemia can also be caused by lupus. It happens when the body has less red blood cells. For people with lupus, this can be due to inflammation, bleeding, or the immune system attacking them.
Memory problems or trouble thinking, often called “brain fog” can happen when someone has had lupus for a few years. Inflammation or lack of oxygen to parts of the brain cause problems with cognitive function. You may also experience changes in behavior, hallucinations, or have a hard time expressing your thoughts.
慢性疼痛障碍,fibromyalgia, may co-occur with lupus and other autoimmune disorders. Fibromyalgia causes chronic pain, tenderness, fatigue, irritable bowels, and trouble sleeping. It can be responsible for the pain felt by people with lupus. It’s thought to be caused by changes in the pathways that lead to the brain and spinal cord, or the sensors for pain within the brain.
Headaches that feel like migraines, often called lupus headaches, can be caused by inflamed blood vessels around the brain.
您的免疫系统旨在保护您的身体免受伤害。健康的免疫系统攻击异物,如细菌,病毒和感染,让你生病。
狼疮,如其他自身免疫疾病,来自免疫系统的失常和攻击身体健康组织的结果。这些对身体健康组织的攻击可能会随着时间的推移而导致永久性损害。
在某些区域发生的炎症是攻击物质的白细胞的结果。当白细胞正在攻击异物时,一旦入侵者消失,炎症就会消失。如果他们看到健康的组织作为威胁,那么炎症将继续攻击。炎症本身可引起疼痛和长期瘢痕,导致永久性损害。
Your digestive system moves food through the body, taking nutrients in, and getting rid of waste. This process starts at the mouth and goes through the intestines. Lupus, and some medications used to manage symptoms, can cause side effects in the digestive system.
由狼疮引起的食管炎症可以触发胃灼热。
消化系统的问题,如恶心,呕吐,腹泻和便秘通常是用于治疗狼疮的药物的症状。Nonsteroidal anti-inflammatory drugs (NSAIDs),采取对狼疮和其他慢性病的人的疼痛,也可以增加胃衬里出血溃疡的风险。
Your liver helps with digestion and removes alcohol and other substances from the blood. Inflammation in the liver can stop it from working properly, causing blood clots in the vessels bringing blood to the liver, and resulting in an enlarged liver.
Lupus can also cause your immune system to attack joints, causing pain and arthritis. When joints become inflamed, it causes pain and long-term damage. Lupus arthritis can occasionally affect large joints, like knees and hips, but more commonly affects smaller joints, like in the hands and wrists.
Some medications used to treat lupus can cause bone loss or osteoporosis. This leaves you vulnerable to bone fractures and breaks.
Having lupus puts you at a higher risk of developing infections and getting pneumonia.
Inflammation and fluid buildup in or around the lungs can create a variety of different complications for people with lupus. It can also cause chest pain when you take a deep breath.
Lupus doesn’t directly affect your reproductive organs, but the disease can cause complications during pregnancy. A pregnancy with lupus is considered high risk and requires more frequent doctor’s visits for monitoring. Risks include:
- 流产
- premature deliver
- preeclampsia
宝宝也可以出生在新生儿狼疮综合征,这种情况影响心跳并导致皮疹。
However, a woman with lupus most often gives birth to a healthy baby. She may just need additional care from her doctor during the pregnancy.
Your kidneys are extremely important for maintaining good health. They help remove waste from the blood, regulate blood volume and pressure, and filter waste out through urine.
肾脏问题在狼疮的人们中常见,通常是在肾脏中长期炎症带来的。肾病的症状包括:
- blood in the urine
- 腹部肿胀
- 腿或脚踝肿胀
- nausea and vomiting
虽然狼疮确实有能力在整个身体中引起症状,但这并不意味着你会遇到所有这些。
你个人的症状及其严重程度将depend on the type of lupus you have and other factors. These include your genetics and how long you’ve had the disease. If your lupus is well-controlled, you may have very mild symptoms.