Hidradenitis suppurativa (HS) is an auto-inflammatory disease in which hair follicles fill with bacteria, keratin, and sweat. This buildup can cause painful lesions and abscesses containing pus. It’s unclear what causes the condition.

Crohn’s disease is a form of inflammatory bowel disease (IBD). It can cause inflammation anywhere throughout the digestive system. This affects how the body absorbs nutrients. Symptoms include cramping, bleeding, and diarrhea.

一次，这些条件被视为完全无关。但 research 现在表明存在一些潜在的连接。

People who live with HS are more likely to develop Crohn’s disease. If you have HS, it’s a good idea to be aware of the signs of Crohn’s. It’s important to get the right diagnosis and treatment to manage your day-to-day life with these conditions.

Crohn的疾病和HS都是炎症条件，它们从免疫反应开始。免疫系统旨在瞄准伤害或入侵者。

When the immune system is triggered, it increases blood flow to the area to bring in more immune cells. This is a good thing if the target is something harmful, like pathogenic bacteria.

在某些情况下，炎症在身体内触发，没有明显的原因，并没有关闭。结果可以是肿胀，疼痛和身体健康区域的损害。正在进行中researchexploring how inflammatory conditions may all be related.

一种nother possible link between these conditions involves changes in your microbiome. The microbiome refers to the trillions of microscopic living organisms in and on our bodies. The majority live in our digestive system, but many also live on our skin.

有克罗恩病和HS的人的微生物体有变化。克罗恩病的人在肠道中的细菌菌落变化。在皮肤，毛囊和汗腺中的HS，细菌和汗腺中可能引发炎症。

For both conditions, it’s unclear what happens first. Does the microbiome change, increasing the risk for disease? Or does the disease result in changes to the microbiome?

一种2017 studyalso suggests that smoking can increase your risk for both conditions. For people who already have HS or Crohn’s disease, smoking can make symptoms worse.

早期阶段的HS的症状可以与其他皮肤状况相似，甚至可以被误诊为严重痤疮。它被认为会影响1 percentof people.

People with HS are 更倾向于 与一般人群相比，让克罗恩病了。当您有HS时，其他炎症条件也存在增加的风险。

一种large meta-analysis from 2019 looked at the connection between Crohn’s disease and HS. They found an over twofold greater incidence of Crohn’s disease in people with HS.

这两个条件都会影响肛周区域（肛门周围的皮肤），病变看起来非常相似。由于医疗保健专业人员可能认为病变与克罗恩有关，有可能忽略了一些HS病例。

如果您与HS等慢性条件一起生活，则无法监控任何健康变化很重要。它总是最好尽早找到事情。与您的医生讨论您的疑虑，以便他们可以在正确的待遇开始。

Painful abscesses can occur in the perianal area as part of HS or Crohn’s disease. If you have HS and have skin symptoms in that area, it’s recommended that you see a gastroenterologist (a doctor who specializes in the digestive system). They can better assess if it’s part of your HS or another issue.

Here are some common signs and symptoms of Crohn’s disease:

  • abdominal cramping
  • blood in the stool
  • nausea and vomiting
  • severe diarrhea
  • 低铁水平（贫血）
  • 疲劳
  • low appetite
  • unexplained weight loss

There’s no specific test to diagnose Crohn’s disease, and other conditions can cause similar symptoms.

您的医生会询问您的医疗和家庭历史。他们还会询问您有关您症状的更多详细信息。之后，他们可以订购以下一个或多个测试：

  • 验血。一种high white blood cell count revealed in a blood test may indicate inflammation or an infection. Low red blood cells may be a sign of blood loss or anemia, which is common in Crohn’s disease.
  • Stool test.粪便测试可以寻找炎症的迹象。它还可以筛选寄生虫或其他感染来源。
  • Upper endoscopy.这是一个测试，它使用带有光和相机的小灵活范围。医生通过消化系统的上部引导它。可以检查食道，胃和小肠损伤或炎症。
  • Capsule endoscopy.To do this test, you swallow a small pill with a camera inside. It takes pictures of your entire digestive tract. This test won’t be done if you have narrowing in any part of your digestive tract.
  • 结肠镜检查。结肠镜检查是一种寻找损坏或炎症的其他范围。它探讨了消化道的下半部分，包括直肠，大肠（结肠）和小肠的下部。

There are different medications available to reduce the immune response and improve symptoms.Your treatment plan will depend on the symptoms and severity of your disease.

Crohn’s disease and HS share some of the same inflammatory proteins. Some biologic medications can be used to treat both conditions.这些包括：

  • 一种dalimumab (Humira).This injectable medication is a type of anti-tumor necrosis factor-alpha therapy (anti-TNF). It stops the action of specific proteins released by the immune system. It’s shown to reduce disease activity in both HS and Crohn’s.
  • Ustekinumab（Stelara）。This medication is a type of monoclonal antibody. It’s an established treatment for Crohn’s disease. More recently, it’s 已经显示出来 to help with HS symptoms. This medication targets IL-12 and IL-23 proteins. Higher levels of these inflammatory proteins are found in both Crohn’s disease and HS.
  • Guselkumab（Tremfya）。This medication targets the IL-23 protein to reduce inflammation. There have been 实例探究 showing it’s effective for both HS and Crohn’s disease. However, more research is needed.

可能成为您的治疗部分的其他药物包括：

  • 皮质类固醇。这种类型的药物可减少炎症并有助于减轻免疫应答。这些药物用于各种炎症条件。
  • 一种ntibiotics.These may be used to treat an infection.

专门针对克罗恩病的其他治疗包括：

  • sulfasalazine and 5-aminosalicylates (5-ASA)
  • anti-diarrhea therapies
  • surgery

Other treatments for HS include:

  • oral retinoid medications
  • 抗炎药
  • 局部乳霜
  • 激光除毛

People with HS have a greater higher chance of developing Crohn’s disease. Both are inflammatory diseases. A change in the microbiome may also contribute to these conditions.

观察消化健康的任何变化是明智的。如果您注意到新症状，请与您的医生交谈。他们可能会将您提及胃肠学家，以帮助确保您获得正确的诊断和治疗。