A tumor is a growth of tissue that happens when cells in your body grow and divide at a faster rate than they would normally. When we think of tumors, we often think of cancer. However, not all tumors are malignant (cancerous).
脱粘性肿瘤是从结缔组织形成的一种良性（非癌）肿瘤。这些类型的肿瘤可以在整个身体的许多地方，包括腹部的壁。
Continue reading to learn more about these tumors, what symptoms they cause, and how they’re treated.
Adesmoid tumor是一种起源于结缔组织的良性肿瘤。结缔组织是有助于将器官固定在适当的组织的类型，并为您的肌肉，骨骼和韧带提供支撑。
Desmoid tumors do not metastasize, meaning that they cannot spread to other areas of the body. However, they can still grow into surrounding tissue. This can lead to potentially serious complications and make them harder to remove.
There are three types of desmoid tumors. These are classified by where in the body the tumor begins.
- 腹部肿瘤。腹部脱粒肿瘤是在腹壁中形成的肿瘤。腹壁包括包围腹腔的组织，其中许多内脏所在。
- Intra-abdominal tumor.这些脱粒肿瘤在连接腹腔内器官的组织中形成。
- 腹外肿瘤。These desmoid tumors occur in connective tissue found in other areas, such as the shoulders, upper arms, and thighs
As a whole, desmoid tumors are rare, affecting only
The symptoms that you experience with an abdominal desmoid tumor can vary depending on such factors as:
- 肿瘤的大小
- where exactly it’s located
- how fast it’s growing
If you have an abdominal desmoid tumor, you may notice a肿胀或肿块on your abdomen. This lump typically feels firm and can sometimes be painless.
However, as the tumor grows, it can begin to affect surrounding tissues, such as muscles and nerves. When this happens, an abdominal desmoid tumor can become very痛苦。This can interfere with sleep and other daily activities.
Additional symptoms of abdominal desmoid tumors typically arise due to complications, which can be potentially serious. See below for more information on potential complications.
当肿瘤成长并破坏附近的组织时，腹部脱粒肿瘤的并发症发生。
肠梗阻
通常与腹部脱粒肿瘤有关的并发症是肠梗阻，这是医疗紧急情况。当发生这种情况时，您可能会遇到以下症状：
如果您遇到这些类型的症状，请立即与医生联系。
输尿管阻塞
可能发生的另一个并发症是ureter obstruction这是从肾脏到膀胱的管道被堵塞的时候。这可能会导致肾脏损伤，并可能引起腹部疼痛等症状尿量减少。
Don’t hesitate to contact a doctor if you’re experiencing these symptoms.
脱粒肿瘤来自一种称为成纤维细胞的细胞。这些细胞是结缔组织的成分，并在愈合伤口中起作用。
目前尚不知道是什么原因导致这些细胞开始生长和分裂失控。但是，遗传学似乎起着重要作用。
About85％脱粘性肿瘤的突变在一个称为的基因中CTNNB1。该基因编码对于控制与细胞生长有关的基因很重要的蛋白质。
Desmoid tumors, particularly abdominal desmoid tumors, also happen more often in people with a genetic condition called familial adenomatous polyposis (FAP). FAP is associated with the development of cancers in thecolon and rectum。
除了拥有FAP外，其他一些腹部脱粒肿瘤的危险因素还包括：
- 出生时被分配
- 年轻的年龄，峰值发生在30至40岁之间
- pregnancy
- 暴露于高水平的雌激素
- 以前的腹部受伤或手术
有些患有腹部脱粒肿瘤的人可能不会出现症状。因此，在筛查或测试其他影响腹部的健康状况时可能会发现肿瘤。
如果您确实有症状，您的医生将首先请求您的病史并进行身体检查。他们会询问您的症状，刚开始的时候，如果有任何事情会使它们变得更好或更糟。
They will then order imaging tests to get a look at the tumor, its size, and where it’s located. Several different types of imaging technology may be used, including:
为了确认您的肿瘤是一种脱蛋白肿瘤，而不是另一种肿瘤类型，您的医生也会服用活检。这是可以在显微镜下在实验室中分析的肿瘤的组织样品，以确定您的肿瘤类型。
如果您患有腹部脱粒肿瘤并且没有症状，您的医生可能会建议注意等待，在此期间，他们会随着时间的推移继续监测您的肿瘤。一些脱粒肿瘤可能会自行收缩。
治疗is typically initiated when an abdominal desmoid tumor is causing symptoms or is steadily growing larger.
手术
治疗腹部脱粒肿瘤的主要方法是手术。目的是清除尽可能多的肿瘤。手术后，通常需要使用假肢网状物进行重建腹壁的影响部分。
其他治疗方法
如果不是手术，则还可以在医学上治疗腹部脱粘性肿瘤。这些类型的治疗可能包括：
- 化学疗法。化学疗法药物靶向并破坏迅速生长的细胞，例如在肿瘤中发现的细胞。某些类型化学疗法可以有效地抵抗脱粘性肿瘤。
- 有针对性的疗法。Targeted therapy drugs disrupt specific proteins important for tumor growth. Pazopanib (Votrient）和索拉非尼（Nexavar) are two targeted therapy drugs that may benefit people with desmoid tumors.
- Radiation.该治疗方法涉及使用高能辐射破坏肿瘤细胞。Radiationmay also be used to remove remaining tumor cells following surgery. This is called adjuvant therapy.
- 激素疗法。因为脱粘性肿瘤的生长似乎与激素，特别是雌激素，激素治疗，例如tamoxifen可能有助于脱粒肿瘤。
- 非甾体类抗炎药（NSAIDS）。一些NSAID努力抑制参与脱粘性肿瘤生长的途径，可用于治疗脱粘性肿瘤。示例包括苏莱达克和美洛昔康。
腹部脱粒肿瘤的前景可能因个体而异。影响前景的因素包括：
- 肿瘤的大小
- how fast it’s growing
- where in your abdomen it’s located
- 是否可以通过手术去除
一般而言，腹部脱粒肿瘤通常可以通过手术去除时反应良好。
For example, a
Overall, your doctor can give you the best information on your outlook and what to expect from treatment. If you have any questions or concerns, don’t hesitate to discuss them.
Abdominal desmoid tumors are benign tumors that originate from connective tissue. They can sometimes grow into surrounding tissue, which can lead to potentially serious complications.
如果您发现腹部区域有无法解释的肿块或肿胀，请务必立即去看医生，尤其是在疼痛时。