Overview

Pemphigoid是一种罕见的自身免疫疾病，可以在任何年龄发生，包括在儿童中，但最常常影响老年人。猪眼是由免疫系统的故障引起的，并导致皮疹和腿部，臂和腹部起泡。

猪眼也可以在粘膜上引起起泡。粘膜产生粘液，有助于保护身体内部。Pemphigoid可以在眼睛，鼻子，嘴巴和生殖器中找到粘膜。它也可以在一些女性怀孕期间发生。

There’s no cure for pemphigoid, but there are various treatment options.

所有类型的猪眼是由免疫系统攻击健康组织引起的。他们出现了鲁莽and填充流体的水泡。The types of pemphigoid differ in terms of where on the body the blistering occurs and when it occurs.

大疱性类天疱疮

In cases of bullous pemphigoid — the most common of the three types — the skin blistering happens most commonly on the arms and legs where movement occurs. This includes the areas around the joints and on the lower abdomen.

CicaTricial Pemphigoid.

CicaTricial Pemphigoid., also called mucous membrane pemphigoid, refers to blisters that form on the mucous membranes. This includes the:

  • mouth
  • eyes
  • nose
  • 喉
  • 生殖器

受影响的最常见的位点是嘴巴和眼睛。皮疹和起泡可以在其中一个区域中开始，如果未经处理，则可以蔓延到其他区域。如果它在眼中未经处理过的情况，它可能导致疤痕，这反过来可能导致失明。

Pemphigoid.gestationis

当怀孕期间或不久发生起泡时，它被称为Pemphigoid Gestationis。虽然它与疱疹病毒无关，但它被称为疱疹妊娠。

The blistering typically develops during the second or third trimester, but may occur at any time during pregnancy, or up to six weeks after delivery. Blisters tend to form on the arms, legs, and abdomen.

Pemphigoid是一种自身免疫性疾病。这意味着您的免疫系统错误地开始攻击您的健康组织。在发汗剂的情况下，免疫系统会产生抗体，以攻击在外部皮肤层下方的组织。这导致皮肤层分开并导致疼痛起泡。它尚未完全理解为什么免疫系统在用猪疱疹的人中做出这种反应。

在许多情况下，也没有针对Pemphigoid的特定触发。但是，在某些情况下，可能是由以下方式引起的：

  • 某些药物
  • radiation therapy
  • ultraviolet light therapy

People with other autoimmune disorders are found to be at a higher risk for developing pemphigoid. It’s also more common in the elderly than in any other age group, and seems to occur slightly more in women than men.

The most common symptom of pemphigoid is blistering that occurs on the arms, legs, abdomen, and mucous membranes.Hivesand瘙痒也很常见。泡罩具有某些特性，无论它们的身体都在哪个位置：

  • 在水疱之前发出红色皮疹
  • 水泡很大并充满了通常清晰的流体，但可能含有一些血液
  • 水泡很厚，不易破裂
  • 水疱周围的皮肤可能看起来正常，或略微红色或黑暗
  • 破裂的水泡通常是敏感和痛苦的

您的皮肤科医生will be able to make a fairly firm diagnosis simply by examining your blisters. Further testing will be needed to prescribe the right treatment.

您的doctor may want to perform askin biopsy, which involves removing small samples of skin from the affected areas. Lab technicians will test these samples for the immune system antibodies characteristic of pemphigoid. These antibodies can also be detected in your blood, so you may need to have a small sample of blood drawn.

Pemphigoid.cannot be cured, but treatments are usually very successful at relieving symptoms. Corticosteroids, either in pill or topical form, will likely be the first treatment your doctor prescribes. These medications reduce inflammation and can help to heal the blisters and relieve itching. However, they can also cause significant side effects, especially from long-term use, so your doctor will taper you off of the corticosteroids after the blistering clears up.

另一种治疗方法是服用抑制免疫系统的药物，通常与皮质类固醇结合。免疫抑制剂帮助，但他们可能会让您面临其他感染的风险。也可以规定某些抗生素，例如四环素，以降低炎症和感染。

通过综合治疗，Pemphigoid的前景很好。大多数人对药物做好反应。疾病经常在几年的治疗后消失。但是，即使有适当的治疗，Pephigoid可能随时返回。

如果您培养任何无法解释的起泡，请参阅您的医生。及时诊断和治疗将有助于更快地管理此条件。