目前，没有治愈强直性脊柱炎（AS）。但是，大多数患者可以持久，生产的生活。
由于症状开始与疾病的确认之间的时间，早期诊断至关重要。
Medical management, ancillary care therapies, and targeted exercises can offer patients improved quality of life. Positive impacts include pain relief, increased range of motion, and increased functional capacity.
The most promising clinical trials are those examining the efficacy and safety of bimekizumab. It’s a drug that inhibits both interleukin (IL)-17A and IL-17F — small proteins that contribute to AS symptoms.
Filgotinib杰纳斯(FIL)是一种选择性抑制剂kinase 1 (JAK1), another problematic protein. FIL is currently in development for treatment of psoriasis, psoriatic arthritis, and AS. It’s taken orally and is very potent.
Your eligibility to participate in a clinical trial for AS depends on the purpose of the trial.
试验可能研究调查药物的疗效和安全性，骨骼受累的进展，或疾病的自然过程。对诊断标准的修订，以影响未来临床试验的设计。
The latest FDA approved drugs for treatment of AS are:
- Ustekinumab（Stelara），IL12 / 23抑制剂
- Tofacitinib（Xeljanz），jak抑制剂
- Secukinumab（Cosentyx），IL-17抑制剂和人源化单克隆抗体
- Ixekizumab（Taltz），IL-17抑制剂
我经常建议的互补疗法包括：
- 按摩
- acupuncture
- 痛苦
- 水疗练习
Specific physical exercises include:
- 伸展
- 墙坐
- 木板
- 下巴躺在躺椅上
- 臀部伸展
- 深呼吸锻炼和散步
还鼓励使用瑜伽技术和经皮电子神经刺激（TENS）单位。
Surgery is rare in AS. Sometimes, the disease progresses to the point of interfering with daily activities because of pain, limitations of motion, and weakness. In these cases, surgery might be recommended.
There are a few procedures that can decrease pain, stabilize the spine, improve posture, and prevent nerve compression. Spinal fusion, osteotomies, and laminectomies performed by very skilled surgeons can be beneficial to some patients.
这是我的印象，即根据具体的临床发现，改善的成像技术和这种疾病的任何相关表情，将根据具体的临床发现量身定制。
如落在更广泛类别的疾病的伞下，称为脊椎内疾病。这些包括牛皮癣，银屑病关节炎，炎症性肠病和反应性脊椎病。
There can be crossover presentations of these subsets and people will benefit from a targeted approach to treatment.
两个特定基因，HLA-B27和ERAP1可以参与表达式。我认为将通过了解它们的互动和与炎症性肠疾病的关联方式来了解的下一个突破。
一个主要的进步是纳米医生。该技术已被用于成功治疗骨关节炎和类风湿性关节炎等其他炎症疾病。基于纳米技术的递送系统的开发可能是令人兴奋的管理。
Brenda B.Spriggs，MD，FACP，MPH，是临床教授Emerita，UCSF，风湿病学，几个医疗保健组织的顾问和作者。她的兴趣包括患者宣传和对医生和服务不足的人口提供专家风湿学咨询的热情。她是“专注于你最好的健康的共同作者：你应得的医疗保健智能指南”。