Acrocyanosis is a painless condition that causes the small blood vessels in your skin to constrict. This turns the color of your hands and feet bluish.

The blue color comes from the decrease in blood flow and oxygen moving through the narrowed vessels to your extremities (outer limbs).

Acrocyanosis is common in newborns. Most other people with the condition are teens and young adults.

Medical scientists first coined the term in 1896, according to a 2016 research review , but acrocyanosis is still not well understood or studied.

There are two types of acrocyanosis: primary and secondary.

原发性胶结酶有与寒冷温度和情绪应激的联系。医生不认为这是有害的。

Secondary acrocyanosis develops due to many different underlying diseases, according to2011 research. These include eating disorders, psychiatric illnesses, and cancer.

The term “acrocyanosis” comes from the Greek words “akros” (extreme) and “kyanos” (blue).

Hands and feet are the extremities most often affected by acrocyanosis. But its symptoms can develop in several different areas, including your:

  • wrists
  • ankles
  • 鼻子
  • 耳朵
  • lips
  • nipples

The symptoms are symmetrical in primary acrocyanosis, affecting both hands or both feet. In secondary acrocyanosis, symptoms often affect only one side, may be painful, or may involve tissue loss.

The most common symptoms are:

  • bluish-colored fingers or toes
  • cold, clammy, and sweaty hands and feet
  • lower skin temperatures and blood flow
  • swelling of hands and feet
  • 一个“正常”脉冲

Symptoms worsen with cold and improve with warmth. Finger color goes back to usual when you move your hands to a horizontal position, from hanging down.

Most newborns have blue hands and feet right after birth and in their first few hours, according toexperts.

The acrocyanosis symptoms may come back when the baby is cold or when the baby first comes out of a bath. However, the condition doesn’t persist in infants.

What does acrocyanosis look like?

患有胶结性的人可能有以下几个如下:

Primary acrocyanosis

There isn’t much specific research on the causes of acrocyanosis. A 2011 study 据报道,医学界缺乏清晰度关于胶结性是否是单一疾病或因原因而变化的条件。

The current understanding around primary acrocyanosis is that it occurs due to the constriction of small blood vessels. This decreases the flow of oxygen-rich blood to your extremities.

这种收缩或血管痉挛可能有一些发展的原因,包括:

  • cold temperatures
  • living in a high altitude with a combination of lower oxygen pressure, increased wind, and cold
  • a genetic anomaly that affects your blood vessels

As newborns get used to the change in blood circulation between the womb and the outside world, they might show signs of acrocyanosis. At first, oxygen-rich blood circulates to the brain and other organs rather than the hands and feet.

However, it’s hard to confirm the true root of acrocyanosis until more research takes place.

Secondary acrocyanosis

There is more research around secondary acrocyanosis because studies have examined the underlying primary diseases. In some cases, acrocyanosis may be the first sign of the primary disease.

The causes of secondary acrocyanosis vary widely and include:

  • vascular disorders
  • infections
  • 血液疾病
  • solid tumors
  • genetic diseases
  • some medications

Specific health factors that cause second acrocyanosis

Different conditions can trigger the effects of acrocyanosis in different ways, including:

  • Raynaud’s phenomenon.This is the most common underlying cause, in which the extremities turn pale, then blue, then red.
  • 厌食症。当一个人与厌食症一起生活时,体重减轻可能会损害他们的身体的热调节。估计21到40%of people with anorexia have acrocyanosis.
  • Ergot alkaloid drugs.人们用这些来治疗偏头痛发作和头痛。但其副作用之一是胶结性。
  • Chikungunya.This mosquito-borne viral infection can cause acrocyanosis.
  • Various types of cancers.Up to24 percentof people with cancer have acrocyanosis.

Your doctor will ask you about your medical history and symptoms, then conduct a physical examination. They will base your diagnosis of primary acrocyanosis on your hands and feet (and sometimes nose and ears) being:

  • blue-colored
  • pain-free
  • cold
  • sweaty

医生还可以订购毛细管镜检查,这是一种非侵入性的技术,可以测量美甲床的小船只中的循环。

They may perform otherteststo rule outRaynaud’s phenomenonchilblains, two conditions that also involve bluish extremities. Having a “normal” pulse indicates that the blue tint has not occurred due to an arterial disease that reduces blood circulation.

If your physician suspects secondary acrocyanosis, they will order other laboratory testing and imaging procedures to determine the underlying disease.

The majority of people with primary acrocyanosis won’t require treatment.

Primary acrocyanosis

对原发性胶结性没有标准治疗。很少有临床试验看过治疗的有效性。

However, doctors tend to use some of the following approaches when helping you manage acrocyanosis:

  • Warming measures.With newborns and infants, warming the baby is an effective treatment. Acrocyanosis is common in infants and not especially harmful. For others, a healthcare professional will likely advise you tokeep your hands and feet warmindoors and to protect yourself against exposure to cold temperatures.
  • Some medications.In people with severe acrocyanosis, doctors have used alpha-blocker andcalcium channel blocker drugs, topical nicotinic acid derivatives, or minoxidil to ease symptoms.
  • Reassurance and patience.The medical literature stresses that it’s important for doctors to reassure their patients that the condition is not harmful.

Secondary acrocyanosis

Treating the underlying disease may improve the symptoms of acrocyanosis.

If your symptoms are occurring due to medication like anergot alkaloid, you might benefit from speaking with your doctor about other medications or treatments if you have concerns about acrocyanosis and other side effects.

原发性胶结性是一种罕见和良性的条件,良好的前景。有些治疗方法可以在严重案件中减少症状。

In newborns, acrocyanosis is typical and resolves without treatment.

Secondary acrocyanosis can be serious, depending on the underlying cause. See your doctor if you have symptoms of acrocyanosis. They can determine whether there’s an underlying condition that needs treatment.